CV - DUALE Christian


Dr. Christian Dualé




Hospital practitioner


  • M.B (Anaesthesia & Intensive Care, Université d’Auvergne, Clermont-Ferrand, 1992)
  • M.S. in Neuroscience (Université Pierre et Marie Curie, Paris VI, 1995)
  • Ph.D. in Neuroscience (Université d’Auvergne, Clermont-Ferrand, 2000)
  • M.D. (Certificate of aptitude to direct research projects and students, Université d’Auvergne, Clermont-Ferrand, 2005).
  • Certificate of training in interpretation of clinical trials, Université Claude-Bernard, Lyon, 2008.



CPC-CIC, Bâtiment 3C, 58 rue Montalembert, BP 69, 63003 Clermont-Ferrand Cedex 01


+33 4 73 17 84 18

Research Interest:

Concomitantly to my medical practice in the field of anaesthesia and intensive care, I have been involved in the pain research team (directed by Pr A. Woda then Pr R. Dallel) at Clermont-Ferrand since 1992. While my first topic was focused on the role of opioids in nociception at the trigeminal level, I conducted clinical trials in the field of early postoperative analgesia and of perispinal analgesia for labour. Since 2003, I focused on postsurgical neuropathic pain, especially in its epidemiological and mechanistic aspects. Since 2006, I work in Clinical Pharmacology as the associate coordinator of the Clinical Investigation Centre of the University Hospital of Clermont-Ferrand. My actual interests in research are:

­          risk factors of postsurgical neuropathic pain;

­          non-steroidal anti-inflammatory drugs and pain at movement;

­          improving the monitoring of intraoperative pain/analgesia;

­          improving the relevance of clinical trials on postoperative pain/analgesia: outcomes, methods of comparison.

Technical expertise:

­          Various fields of medicine, as anaesthetist/intensivist.

­          Designing clinical trials.

­          Ethics and regulation in clinical research.

Recent Publications:

  • Bazin M, Bonnin M, Storme B, Bolandard F, Vernis L, Lavergne B, Pereira B, Bazin JE, Dualé C. Addition of clonidine to a continuous patient-controlled epidural infusion of low-concentration levobupivacaine plus sufentanil in primiparous women during labour. Anaesthesia. 2011 Sep;66(9):769-79.
  • Eljezi V, Dualé C, Azarnoush K, Skrzypczak Y, Sautou V, Pereira B, Tsokanis I, Schoeffler P. The analgesic effects of a bilateral sternal infusion of ropivacaine after cardiac surgery. Reg Anesth Pain Med. 2012 Mar-Apr;37(2):166-74.
  • Dualé C, Guastella V, Morand D, Cardot JM, Aublet-Cuvelier B, Mulliez A, Schoeffler P, Escande G, Dubray C. Characteristics of the neuropathy induced by thoracotomy: a 4-month follow-up study with psychophysical examination. Clin J Pain. 2011 Jul-Aug;27(6):471-80.
  • Dualé C, Ouchchane L, Schoeffler P; EDONIS Investigating Group, Dubray C. Neuropathic aspects of persistent postsurgical pain: a French multicenter survey with a 6-month prospective follow-up. J Pain. 2014 Jan;15(1):24.e1-24.e20.
  • Dualé C. Prolonged use of opioids after surgery. BMJ. 2014 Feb 11;348:g1280.
  • Dualé C, Nicolas-Courbon A, Gerbaud L, Lemery D, Bonnin M, Pereira B. Maternal satisfaction as an outcome criterion in research on labour analgesia: data analysis from the recent literature. Clin J Pain. 2015 Mar;31(3):235-46.
  • Cherprenet AL, Rambourdin-Perraud M, Laforêt S, Faure M, Guesmi N, Baud C, Rosset E, Schoeffler P, Dualé C. Local anaesthetic infiltration at the end of carotid endarterectomy improves postoperative analgesia. Acta Anaesthesiol Scand. 2015 Jan;59(1):107-14.
  • Dualé C, Julien H, Pereira B, Abbal B, Baud C, Schoeffler P. Pupil diameter during post-anesthetic recovery is not influenced by postoperative pain, but by the intraoperative opoid treatment. J Clin Anesth. 2015 Feb;27(1):23-32.
  • Deschaumes C, Devoize L, Sudrat Y, Baudet-Pommel M, Dualé C, Dallel R. Relationship between resting arterial blood pressure and oral postsurgical pain. Clin Oral Investig. 2014 Nov 18. [Epub ahead of print]
  • Dualé C, Gayraud G, Taheri H, Bastien O, Schoeffler P. A French nationwide survey on anesthesiologist-perceived barriers to the use of epidural and paravertebral block in thoracic surgery. J Cardiothorac Vasc Anesth. 2014 Nov 11. pii: S1053-0770(14)00544-8. doi:10.1053/j.jvca.2014.11.006. [Epub ahead of print].
  • Niccolaï P, Ouchchane L, Libier M, Beouche F, Belon, M, Vedrinne JM, El Drayi B, Vallet L, Ruiz F, Biermann C, Duchêne P, Chirat C, Soule-Sonneville S, Dualé C, Dubray C, Schoeffler P. Persistent neuropathic pain after inguinal herniorraphy depending on the procedure (open mesh vs. laparoscopic). A propensity-matched analysis. Can J Surg. 2015 Apr; 58(2):114-20.
  • Lefebvre-Kuntz D, Dualé C, Albi-Feldzer A, Nougarède B, Falewee MN, Ouchchane L, Soule-Sonneville S, Bonneau J, Dubray C, Schoeffler P. General anaesthetic agents do not influence persistent pain after breast cancer surgery. Results from a nationwide prospective cohort study. Eur J Anaesth. 2015 Feb 13. [Epub ahead of print]
  • Richez B, Ouchchane L, Guttmann A, Mirault F, Bonnin M, Noudem Y, Cognet V, Dalmas AF, Brisebrat L, Andant N, Soule-Sonneville S, Dubray C, Dualé C, Schoeffler P. The role of psychological factors in persistent pain after caesarean section. J Pain. 2015 Aug 20. pii: S1526-5900(15)00815-9. doi: 10.1016/j.jpain.2015.08.001. [Epub ahead of print]

Phone : +33473178418