CV - GONZALEZ TORRECILLA Sandra

Name:

González Torrecilla, Sandra

Nationality

Spanish

Position:

PhD student

Education:

5 years Degree in Psychology

2 years Master’s Degree in Advanced Brain and Behavior Studies

Email:

sandra.gonzalez_torrecilla@etu.uca.fr

Address:

Faculty of Medicine – laboratory neurosensory biophysics

UMR INSERM 1107

28 place Henri Dunant – BP 38 – 63001 Clermont-Ferrand (France)

Phone:

+33 4 73 17 81 30

Research Interest:

One goal of the current project is to establish the part played by the difference between intraocular pressure (IOP) and the intracranial pressure (ICP), that is, the pressure gradient over the lamina cibrosa, in the pathophysiology of glaucoma. A possibly relevant factor of normal tension glaucoma (NTG), which develops in the absence of elevated IOP, might be a lower than average ICP. As the use of invasive ICP assessment via a spinal tap would be unethically risky, we plan to noninvasively evaluate ICP through the ear. Currently, available technology only allows ICP changes to be measured. The first part of the project will be to characterize noninvasively measured ICP changes e.g. with body tilt, or from one day to the next, in patients suffering from clinically proven, lower-than-normal ICP, as compared with normal subjects. In the second part of the project, patients with NTG will be enrolled and their ICP monitored according to the previously established protocol. This will provide insight into the etiology of NTG and ultimately, facilitate treatment decisions in the patients under concern.

Technical expertise:

- Management of clinical trials (neurosurgery, operating room): inclusions, following, validation, reports, etc.

- Animal surgery

- Behavioral techniques

- Psychophysics

- Data analysis

Materials:

- Wide band tympanometry

- Auditory electrophysiology

- Otoacoustic emission